Hanson RG/15/17/31749 Epigenetic Biomarkers and Determinants of Cardiovascular Risk in Children

Staff

Lead researchers

Emeritus Professor Mark Hanson

Connect with Mark

Email: M.Hanson@soton.ac.uk

Other researchers

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

Key research contributions have been:
discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood

Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Professor Keith Godfrey

Associate Dean Enterprise

Connect with Keith

Email: kmg@mrc.soton.ac.uk

Emeritus Professor Hazel Inskip MSc, PhD, FFPH

Connect with Hazel

Email: hmi@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Plants and Food Security

We study the response of plants to the environment at the molecular, whole plant and ecological levels. This includes interactions with nematodes, insects and microbes.

Research outputs

Myo-inositol, probiotics and micronutrient supplementation from preconception for glycemia in pregnancy: NiPPeR international multi-center double-blind randomized controlled trial

Keith Godfrey, Sheila Barton, Sarah El-Heis, Timothy Kenealy, Heidi Nield, Philip N. Baker, Yap-Seng Chong, Wayne Cutfield & Shiao-Yng Chan, 2021, Diabetes Care, 44(5), 1091-1099

DOI: 10.2337/dc20-2515

Type: article

Dietary patterns of five-year-old children and their correlates: findings from a multi-ethnic Asian cohort

Ray Sugianto, Jia Ying Toh, Shu Fang Wong, M.T. Tint, Marjorelee T. Colega, Y.S. Lee, Fabian Yap, Lynette P. Shek, K.H. Tan, Keith Godfrey, Y-S Chong, B.C. Tai & Mary Foong-Fong Chong, 2021, British Journal of Nutrition

DOI: 10.1017/S0007114521001434

Type: article

Neonatal amygdala microstructure mediates the relationship between gestational glycemia and offspring adiposity.

Shirong Cai, Izzuddin M. Aris, Wen Lun Yuan, Kok Hian Tan, Keith Godfrey, Peter D. Gluckman, Lynette Pei-Chi Shek , Yap-Seng Chong, Fabian Yap, Marielle V. Fortier, Michael J. Meaney, Yung Seng Lee & Anqi Qiu, 2021, BMJ Open, 9(1)

DOI: 10.1136/bmjdrc-2020-001396

Type: article

DNA methylation signatures in cord blood associated with birthweight are enriched for dmCpGs previously associated with maternal hypertension or pre-eclampsia, smoking and folic acid intake

Elie Antoun, Philip Titcombe, Kathryn V. Dalrymple, Negusse Kitaba, Sheila Barton, A.C. Flynn, Robert Murray, Emma Garratt, Paul T. Seed, Sara L. White, Cyrus Cooper, Hazel Inskip, Mark Hanson, L. Poston, Keith Godfrey & Karen Lillycrop, 2021, Epigenetics

DOI: 10.1080/15592294.2021.1908706

Type: article

Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

R.C. Huang, P.E. Melton, M.A. Burton, L.J. Beilin, R. Clarke-Harris, E. Cook, K.M. Godfrey, G.C. Burdge, T.A. Mori, D Anderson , S. Rauschert, J.M. Craig, M.S. Kobor, J.L. MacIsaac, A.M. Morin, W.H. Oddy, C.E. Pennell, J.D. Holbrook & K.A. Lillycrop, 2021, Epigenetics

DOI: 10.1080/15592294.2021.1876297

Type: article

Gestational diabetes mellitus and developmental programming

Anne H.Y. Chu & Keith Godfrey, 2021, Annals of Nutrition and Metabolism

DOI: 10.1159/000509902

Type: article

Post-COVID economic recovery: women and children first ...or last?

Neena Modi, Gabriella Conti & Mark Hanson, 2021, Archives of Disease in Childhood, 0, 1-2

DOI: 10.1136/archdischild-2020-320898

Type: letterEditorial