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Research project

Dr Vince O'Connor MRC TSE Highlight

Staff

Lead researchers

Professor Vincent O'connor

Professor of Neurochemistry
Research interests
  • Molecular mechanism of synaptic function and dysfunction
  • Synaptic degeneration
  • Genetic models of synaptic and neuronal dysfunction
Connect with Vincent

Email: V.M.OConnor@soton.ac.uk

Other researchers

Emeritus Professor Hugh Perry MA, DPhil, FMedSci

Connect with Hugh

Email: V.H.Perry@soton.ac.uk

Research outputs

Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease
A.A. Asuni, K. Hilton, Z. Siskova, K. Lunnon, R. Reynolds, V.H. Perry & V. O'Connor, 2010, Neuroscience, 165(3), 662-674
DOI: 10.1016/j.neuroscience.2009.10.047
Type: article
Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology
B.C. Gray, Z. Siskova, V.H. Perry & V. O'Connor, 2009, Neurobiology of Disease, 35(1), 63-74
DOI: 10.1016/j.nbd.2009.04.001
Type: article
Degenerating synaptic boutons in prion disease. Microglia activation without synaptic stripping
Zuzana Siskova, Anton Page, Vincent O'Connor & Victor Hugh Perry, 2009, The American Journal of Pathology, 175(4), 1610-1621
DOI: 10.2353/ajpath.2009.090372
Type: article
C1q: the perfect complement for a synaptic feast?
V. Hugh Perry & Vincent O'connor, 2008, Nature Reviews Neuroscience, 9(11), 807-811
DOI: 10.1038/nrn2394
Type: article
Unaltered SNARE complex formation in an in vivo model of prion disease
Ayodeji A. Asuni, Colm Cunningham, Piranavhan Vigneswaran, V. Hugh Perry & Vincent O'Connor, 2008, Brain Research, 1233, 1-7
DOI: 10.1016/j.brainres.2008.07.083
Type: article
Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization
S. Quraishe, A. Asuni, W.C. Boelens, V. O'Connor & A. Wyttenbach, 2008, Neuroscience, 153(2), 483-491
DOI: 10.1016/j.neuroscience.2008.01.058
Type: article