Research Research groups Member of: Clinical Neurosciences Research projects Active projects Novel Therapeutics for Vision Loss associated with Albinism Researchers: Doctor Helena Lee Doctor James Self , Doctor Arjuna Ratnayaka , Doctor Matthias Baud , Doctor Eloise Keeling Completed projects Medium through-put drug discovery for albinism Researchers: Doctor Eloise Keeling Doctor James Self Sponsor: Fight for Sight Publications 25 publications Page 1 of 3 Could a hand-held, visual electrophysiology device theoretically reduce diagnostic waiting times for complex eye conditions in the NHS? A Discrete Event Simulation (DES) modelling study Steffen Bayer, Daniel Garillo, Marion Penn, Maria (Mary) Chorozoglou, Sally Brailsford, Eloise Keeling, Fatima Shawkat, Perry Carter, Helena Lee & Jay E. Self, 2025, BMC Health Services Research, 25(1) DOI: 10.1186/s12913-025-12551-w Type: article Sigma-2 receptor modulator CT1812 alters key pathways and rescues retinal pigment epithelium (RPE) functional deficits associated with dry age-related macular degeneration (AMD) Britney N. Lizama, Eloise Keeling, Eunah Cho, Evi M. Malagise, Nicole Knezovich, Lora Waybright, Emily Watto, Gary Look, Valentina Di Caro, Anthony O Caggiano, J. Arjuna Ratnayaka & Mary E Hamby, 2025, Scientific Reports, 15(1) DOI: 10.1038/s41598-025-87921-9 Type: article Molecular and cellular mechanisms of levodopa-mediated visual function rescue in albinism Sarah Macdonald, Eloise Keeling, Jennifer A Scott, Helen Griffiths, Andrew Lotery, J. Arjuna Ratnayaka, James Edward Self & Helena Lee, 2024, Investigative Ophthalmology & Visual Science, 65(7) Type: conference Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism Aida Sanchez-Bretano, Eloise Keeling, Jennifer A. Scott, Savannah A. Lynn, Sudha Priya Soundara-Pandi, Sarah L. Macdonald, Tutte Newall, Helen Griffiths, Andrew J. Lotery, J. Arjuna Ratnayaka, Jay E. Self & Helena Lee, 2023, Scientific Reports, 13 DOI: 10.1038/s41598-023-44373-3 Type: article Eyetracking-enhanced VEP for nystagmus Perry Carter, Fatima Shawkat, Jay Self, Helena Lee, Eloise Keeling & Matt Dunn, 2023, Investigative Ophthalmology & Visual Science, 64(8), 43 Type: article Use of a handheld electrophysiology device (RETeval, LKC) to identify visual pathway decussation defects Eloise Keeling, Perry Carter, Fatima Shawkat, Helena Lee & Jay Self, 2023, Investigative Ophthalmology & Visual Science, 64 Type: conference Intraluminal acidity plays a key role in the function of lysosomes in RPE cells Rebecca Denise Miller, Savannah Amy Lynn, Eloise Keeling, Charles Ellis, David Chatelet, David A. Johnston, David Tumbarello, Andrew J. Lotery & Arjuna Ratnayaka, 2023, Investigative Ophthalmology & Visual Science, 64(8) Type: conference Eyetracking-enhanced VEP for nystagmus Perry Carter, Fatima Shawkat, Jay Self, Helena Lee, Eloise Keeling & Matt Dunn, 2023 Type: conference Use of a handheld electrophysiology device (RETeval, LKC) to identify visual pathway decussation defects Eloise Keeling, Perry Carter, Fatima Shawkat, Helena Lee & Jay Self, 2023 Type: conference A high fat "Western-style" diet induces AMD-like features in Wildtype mice Eloise Keeling, Savannah A Lynn, Yen Min Koh, Jenny A Scott, Aaron Kendall, Maureen Gatherer, Anton Page, Felino R Cagampang, Andrew J Lotery & J Arjuna Ratnayaka, 2022, Molecular Nutrition & Food Research, 66(11), e2100823 DOI: 10.1002/mnfr.202100823 Type: article Pagination 1 2 3 Next page Next
