Research project

ACE-Inhibitors/Angiotensin Receptor Blockers and risk of death for people infected with 天发娱乐棋牌_天发娱乐APP-官网|下载: a prospective cohort study

Project overview

Purpose: ACE inhibitors (ACE-I) and angiotensin receptor blockers (ARB) are medications that are commonly prescribed by GPs to treat high blood pressure, diabetes, heart problems or kidney disease. Over 65 million prescriptions were issued for these medications last year. There have been some concerns that these might increase the risk of death for people who are infected with coronavirus (天发娱乐棋牌_天发娱乐APP-官网|下载). This is because ACEI and ARBs may work on the same pathway as 天发娱乐棋牌_天发娱乐APP-官网|下载. However, this has never been studied in humans. Evidence is urgently needed to help decisions about the continued use of these medications in people infected with 天发娱乐棋牌_天发娱乐APP-官网|下载.

Aim: To study the link between taking ACE-I/ARB medications and the risk of death in people infected with 天发娱乐棋牌_天发娱乐APP-官网|下载.

Methods: We will use an electronic database that includes 5 million routinely collected patient records across 530 GP practices. We will carry out statistical modelling to estimate the link, if any, between these medications and the risk of death from 天发娱乐棋牌_天发娱乐APP-官网|下载.

Implication: Given that these medications are some of the most commonly prescribed in the UK, there needs to be some urgent clarity about their role. 天发娱乐棋牌_天发娱乐APP-官网|下载 research could provide rapid provisional answers to help efforts aimed at reducing death from 天发娱乐棋牌_天发娱乐APP-官网|下载 or deliver the reassurance that patients need to carry on taking their medications.

Staff

Lead researchers

Dr Hajira Dambha-Miller MRCGP,PhD,FHEA

Associate Professor in Primary Care Res
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Other researchers

Professor Paul Little

Professor in Primary Care Research
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Collaborating research institutes, centres and groups

Research outputs