Publications

Explore our research outputs and impact in-depth.

Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer

Simon J Crabb, Gareth Griffiths, Ellice Marwood, Denise Dunkley, Nichola Downs, Karen Martin, Michelle Light, Josh Northey, Sam Wilding, Amy Whitehead, Emily Shaw, Alison J Birtle, Amit Bahl, Tony Elliott, Charlotte Westbury, Santhanam Sundar, Angus Robinson, Satinder Jagdev, Satish Kumar, Claire Rooney, Carolina Salinas-Souza, Christine Stephens, Vincent Khoo & Robert J Jones, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2001576

DOI: 10.1200/JCO.20.01576

Type: article

Engineered antibodies to combat viral threats

Mark Cragg & Xiaojie Yu, 2020, Nature, 588, 398-399

DOI: 10.1038/d41586-020-03196-2

Type: article

Tumor-resident stromal cells promote breast cancer Invasion through regulation of the basal phenotype

Christopher Hanley, Elodie Henriet, Orit Katarina Sirka, Gareth Thomas & Andrew Ewald, 2020, Molecular cancer research : MCR, 18(11), 1615–1622

DOI: 10.1158/1541-7786.mcr-20-0334

Type: article

Immune characterization of pre-clinical murine models of neuroblastoma

Emily Webb, Silvia Lanati, Carol Wareham, Alistair Easton, Stuart N. Dunn, Tatyana Inzhelevskaya, Freja M. Sadler, Sonya James, Margaret Ashton-Key, Mark Cragg, Stephen Beers & Juliet Gray, 2020, Scientific Reports, 10(1)

DOI: 10.1038/s41598-020-73695-9

Type: article

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation

Muchaala Yeboah, Charys Papagregoriou, Des C. Jones, Hak Chan, Guangan Hu, Justine McPartlan, Christopher Mockridge, Ivo Tews, Martin Glennie, Stephen Thirdborough, Mark Cragg & Ali Roghanian, 2020, JCI Insight, 5(18)

DOI: 10.1172/jci.insight.141593

Type: article

NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumors

K. Ford, C.J. Hanley, M. Mellone, C. Szyndralewiez, F. Heitz, P. Wiesel, O. Wood, M. Machado, M.-A. Lopez, A.-P. Ganesan, C. Wang, A. Chakravarthy, T.R. Fenton, E.V. King, P. Vijayanand, C.H. Ottensmeier, A. Al-Shamkhani, N. Savelyeva & G.J. Thomas, 2020, Cancer Research, 80(9), 1846-1860

DOI: 10.1158/0008-5472.CAN-19-3158

Type: article

HPV epitope processing differences correlate with ERAP1 allotype and extent of CD8+ T cell tumor infiltration in OPSCC

Emma Reeves, Oliver Wood, Christian Ottensmeier, Emma King, Gareth Thomas, Timothy Elliott & Edward James, 2019, Cancer Immunology Research, 7(7), 1202-1213

DOI: 10.1158/2326-6066.CIR-18-0498

Type: article