Interest in 5-HT signalling associated with immunce cell function and within the wider perspective of immunity has garnered interest following the identification of 5-HT receptors subtypes on almost all immune cells, alongside a number of these receptor subtypes being described as having immunomodulatory functions. However, a deep and detailed characterisation of the all the 5-HT receptor subtypes has yet to be conducted. Additional, the intricate interactions that exist between the nervous system and immune system have become a major point of interest in trying to understand the physiology of both of these systems. In combining the investigation of the role of 5-HT receptor subtypes in cell-specific modulation of immune function, alongside considering the wider perspective of the neuro-immune axis, my current research project aims to develop knowledge in this area to help shed light on the molecular and cellular mechanisms that may underpin various neuro-degenerative, psychiatric and immune disorders. This project benefits from the co-supervision by the industrial partner COMPASS Pathways (https://compasspathways.com/), who are interested in accelerating patients access to evidence-based innovations intended to treat mental health disorders.